Achievements Over A Decade

Service Activities

On a regular basis, the Centre caters to the need of more than 250 biomedical research institutions including public and private enterprises. The Centre has so far bred and supplied over one million laboratory animals to more than 250 biomedical research institutions in the country for basic and applied research.

In addition, standard laboratory animal chow based on locally available ingredients has been developed for rodents, rabbits and monkeys and it is being supplied regularly to various research institutions on request. Also special experimental, feeds as per the requirement like high fat diets, iron and zinc deficient diets etc. are also being supplied.

The Centre regularly supplies blood and blood products from laboratory animals to several research institutions throughout the country.

It has so far trained more than 1500 candidates on various aspects of laboratory animal care, breeding, husbandry, animal experimentation, and ethics under 2 of its regular annual training courses from 1967. It has also trained more than 600 research scientists in the proper use of animals for experimentation under adhoc training programmes over the years.

It has so far conducted 3 international seminars/workshops and held several national seminars over the years. The Centre has brought out 34 volumes of News letter on various aspects of laboratory animal sciences and distributed them on gratis to several research institutes/organizations all over the country. It has brought out a publication called Laboratory Animals User’s Guide which is a ready reckoner for the laboratory animal planners and researchers.

The Centre acted at an advisory capacity in setting up of several new laboratory animal facilities in the country both under private and government sectors as per CPCSEA and AAALAC norms.

Research

The Centre has recently developed 3 mutant obese rat models WNIN ob/ob, WNIN GRob and SD hairless mutant strains for basic research in obesity and associated degenerated diseases like diabetes, cataract, infertility, ageing and dermatological studies. These models have some unique characteristics, which are not seen in similar models available abroad. Centre had collaborative studies with Rockefeller University, New York, US, that are in progress to identify the gene causing obesity in these animals.

The Centre has taken up to collect base line data on clinical biochemical profile along with physiological parameters of various laboratory animals maintained, to supply as a reference material to research workers.

The Centre is a member of the Advanced Pre-clinical toxicological research centre, which is established at NIN, in 2005, to carry out pre clinical toxicological evaluation of drugs, vaccines, nutroceuticals, genetically modified foods for government and private entrepreneurs.

Future Projections

The Centre has created an animal physiology laboratory. Plans are afoot for creating a transgenic and knock out animal facility, meant for research purpose in house as well as outside.

New research projects are being initiated linking obesity with asthma, obesity and iron metabolism, obesogemic diets and their impact on genome, influence of microflora on obesity, obesity and nesfatin (the new satiety molecule identified).